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Evaluating the Role of Mitochondrial Function in Cancer-related Fatigue
Published on: May 17, 2018
Supportive intervention for fatigue in patients undergoing chemotherapy: a randomized controlled trial
Emma Ream1, Alison Richardson, Caroline Alexander-Dann
1Florence Nightingale School of Nursing & Midwifery, King's College London, UK. emma.ream@kcl.ac.uk
Journal of Pain and Symptom Management
|February 21, 2006
Summary
A new supportive intervention significantly reduced chemotherapy-related fatigue, distress, and impact on daily life. Patients reported improved psychological well-being and coping skills, enhancing their ability to manage treatment.
Area of Science:
- Oncology Nursing
- Patient Support
- Quality of Life Research
Background:
- Chemotherapy often causes significant fatigue, impacting patients' quality of life.
- Managing treatment-related fatigue is crucial for patient adherence and well-being.
Purpose of the Study:
- To evaluate a supportive intervention aimed at alleviating fatigue in chemotherapy patients.
- To assess the intervention's impact on fatigue, distress, psychological well-being, and coping mechanisms.
Main Methods:
- A randomized controlled trial involving 103 chemotherapy-naïve patients.
- Intervention included an information pack, fatigue diary, and monthly nurse home visits.
- Support nurses provided fatigue assessment, psychological support, and self-care coaching.
Main Results:
- The intervention group reported significantly less fatigue, distress, and impact on pastimes compared to the control group (P < 0.05).
- Patients receiving the intervention showed significantly lower anxiety and depression levels (P < 0.05).
- The intervention group demonstrated more adaptive coping strategies (P < 0.05).
Conclusions:
- The supportive intervention effectively helped patients adapt to living with chemotherapy-induced fatigue.
- The intervention positively influenced patients' psychological/emotional well-being and coping abilities.
- This approach enhances patients' capacity to manage illness and treatment effectively.
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Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
