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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Phototoxic activity of a thiophene polyacetylene from Leuzea carthamoides
Vladimír Chobot1, Jitka Vytlacilová, Lenka Kubicová
1Department of Pharmaceutical Botany and Ecology, Charles University, Faculty of Pharmacy, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic. vladimir.chobot@faf.cuni.cz
Abstract:
The thiophene polyacetylene (E)-1-[5-(hept-5-en-1,3-diynyl)-2-thienyl]ethan-1,2-diol, isolated from the roots of Leuzea carthamoides, showed phototoxic activity in the assay systems of histidine photo-oxidation, Artemia and Tubifex assays. The effects were compared with the standard photosensitizer xanthotoxin.
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