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Prolonged intensive care unit stay in cardiac surgery: risk factors and long-term-survival
Ortrud Vargas Hein1, Jürgen Birnbaum, Klaus Wernecke
1Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte, Charite-University Medicine Berlin, Berlin, Germany. ortrud.vargas@charite.de
Insights
Identifying risk factors for prolonged intensive care unit (ICU) stay in cardiac surgery patients is crucial. Longer ICU stays correlate with lower long-term survival, emphasizing the need for proactive management.
Area of Science:
- Cardiovascular Surgery
- Intensive Care Medicine
- Outcomes Research
Background:
- Limited research exists on risk factors for prolonged intensive care unit (ICU) stay in cardiac surgery patients, with conflicting findings.
- Cardiac surgery patient populations are increasingly complex, necessitating better risk identification for prolonged ICU courses.
Purpose of the Study:
- To identify preoperative, intraoperative, and postoperative risk factors associated with ICU stays exceeding 3 days in cardiac surgery patients.
- To evaluate the impact of prolonged ICU stay on long-term survival in this patient cohort.
Main Methods:
- Retrospective analysis of 2,683 cardiac surgery patient records.
- Univariate and multivariate analyses were conducted to determine risk factors for extended ICU stay.
- A 3-year follow-up study was performed on 2,563 patients to assess long-term survival.
Main Results:
- Mortality was linked to renal, respiratory, and heart failure, advanced age, elevated APACHE II scores, and reexploration.
- Patients with prolonged ICU stays exhibited significantly lower long-term survival rates.
- However, 6-month to 3-year survival rates were comparable between prolonged and non-prolonged ICU stay groups.
Conclusions:
- Identifying patients at risk for prolonged ICU stays is vital due to increasing cardiac surgery patient acuity.
- Implementing measures to optimize organ function throughout the hospital stay is critical for improving survival and resource utilization.
Background:
Risk factors have been found for prolonged intensive care unit (ICU) stay in cardiac surgery patients in only a few studies; conflicting results have been described. The focus of this study was twofold: first, to evaluate preoperative, intraoperative, and postoperative risk factors for ICU stay greater than 3 days in a cardiac surgery patient population; second, to evaluate long-term survival in cardiac surgery patients with prolonged ICU stay.
Methods:
Records from 2,683 cardiac surgery patients were retrospectively evaluated. Univariate and multivariate analyses for risk factors were performed for an ICU stay greater than 3 days. Thereafter, 2,563 patients were enrolled in a follow-up study for an observational time of 3 years after surgery.
Results:
Mortality was dependent on renal, respiratory, and heart failure, as well as age, elevated APACHE II scores, and reexploration. Long-term survival analyses demonstrated a significantly lower survival in patients with longer ICU stay. However, the 6-month to 3-year long-term survival was comparable with survival in patients without prolonged ICU stay.
Conclusions:
Because of the increasing acuity of patients needing cardiac surgery, it is important to identify those at risk for a prolonged ICU course. It is therefore of paramount interest to implement measures throughout their entire hospital stay that would maximize organ function to improve survival and resource utilization.
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