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Related Experiment Videos

[Silicate urolithiasis: a case report].

C Irisawa1, K Suzuki, H Nakagawa

  • 1Department of Urology, Yamagata Prefectural Central Hospital.

Hinyokika Kiyo. Acta Urologica Japonica
|March 1, 1991
PubMed
Summary
This summary is machine-generated.

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A patient developed silica calculus due to long-term use of anti-acid medication. These silica stones, causing flank pain and urinary issues, were eventually passed spontaneously.

Area of Science:

  • Nephrology
  • Urology
  • Gastroenterology

Background:

  • This case highlights a rare cause of nephrolithiasis: silica calculus.
  • Silica calculus formation is often linked to the prolonged ingestion of specific medications.

Observation:

  • A 62-year-old male presented with left flank pain and urinary retention.
  • Imaging revealed bilateral ureteral and renal stones, with non-visualization of the left kidney.
  • Endoscopy confirmed calculi at the bilateral ureteral orifices, preventing catheter passage.

Findings:

  • The patient had a history of duodenal ulcers and had been taking magnesium silicate and magnesium alminometasilicate for ten years.
  • Analysis confirmed the passed calculi were composed of silica.
  • A review of sixteen similar cases in Japan is included.

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Implications:

  • This case underscores the importance of considering medication history in the etiology of urinary stone disease.
  • Prolonged use of certain antacids may predispose individuals to silica urolithiasis.
  • Further research into the mechanisms of drug-induced silica calculus formation is warranted.