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Shaping up the protein folding funnel by local interaction: lesson from a structure prediction study

George Chikenji1, Yoshimi Fujitsuka, Shoji Takada

  • 1Department of Chemistry, Faculty of Science, Kobe University, Nada, Japan.

Proceedings of the National Academy of Sciences of the United States of America
|February 21, 2006
PubMed
Summary

Fragment assembly (FA) is a successful protein structure prediction method. Local structural preferences, not just sequence-independent compaction, are key to predicting native protein folds.

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