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Published on: July 10, 2012
Colobronchial fistula: a late complication of childhood radiotherapy
G C MacKay1, J Howells, F W Poon
1Department of Radiology, Glasgow Royal Infirmary, Queen Elizabeth Building, 16 Alexandra Parade, Glasgow G31 2ER, Scotland, UK.
Insights
A rare colobronchial fistula, a connection between the colon and bronchial tree, is presented in a 41-year-old man. Previous infant radiotherapy for nephroblastoma is the suspected cause of this unusual condition.
Area of Science:
- Gastroenterology and Pulmonology
- Oncology
- Radiotherapy
Background:
- A 41-year-old male patient with a history of infant radiotherapy for nephroblastoma presented with an unexplained medical condition.
- The patient underwent a barium enema for diagnostic purposes.
Observation:
- The barium enema revealed an abnormal connection, a fistula, between the patient's colon and bronchial tree.
- This colobronchial fistula represents a rare clinical presentation.
Findings:
- Surgical intervention in the form of a right hemicolectomy was performed.
- Pathological examination of the resected colon segment did not reveal any active disease process that could account for the fistula's formation.
Implications:
- The findings suggest that the patient's prior exposure to radiotherapy for nephroblastoma in infancy is the most likely etiological factor for the colobronchial fistula.
- This case highlights a potentially underreported long-term complication of childhood cancer treatment.
- Further investigation into radiotherapy-induced fistulas may be warranted.
Abstract:
We present the case of a colobronchial fistula in a 41-year-old man who underwent radiotherapy for nephroblastoma as an infant. He attended for barium enema, which demonstrated a fistula between colon and bronchial tree. Following right hemicolectomy and pathological examination of the resected bowel, no active disease process was identified to explain the development of this rare fistula. Radiotherapy was deemed the most probable aetiology. We are unaware of this having been previously described.
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