Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Subtle cognitive deficits after cerebellar infarcts.

L S K Hokkanen1, V Kauranen, R O Roine

  • 1Department of Neurology, University of Helsinki, Helsinki, Finland. laura.hokkanen@helsinki.fi

European Journal of Neurology
|February 24, 2006
PubMed
Summary

Cerebellar infarcts can cause subtle cognitive deficits, particularly in working memory. Lesion laterality influences specific symptoms, with left lesions affecting visuospatial tasks and right lesions impacting verbal memory.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thrombolysis and adjunct anticoagulation in patients with acute basilar artery occlusion.

European journal of neurology·2018
Same author

Media multitasking is associated with distractibility and increased prefrontal activity in adolescents and young adults.

NeuroImage·2016
Same author

Three-decade neurological and neurocognitive follow-up of HIV-1-infected patients on best-available antiretroviral therapy in Finland.

BMJ open·2015
Same author

Health outcomes and costs of ischemic stroke patients in Finland.

Acta neurologica Scandinavica·2015
Same author

Symptomatic intracranial haemorrhage after thrombolysis with adjuvant anticoagulation in basilar artery occlusion.

European journal of neurology·2014
Same author

Intravenous thrombolysis in ischemic stroke patients with isolated homonymous hemianopia.

Acta neurologica Scandinavica·2012

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neurology

Background:

  • The cerebellum's role in cognitive functions beyond motor control is increasingly recognized but remains debated.
  • Cerebellar lesions, such as infarcts, can lead to diverse neuropsychological symptoms.
  • The influence of lesion laterality on cognitive deficits requires further investigation.

Purpose of the Study:

  • To investigate the neuropsychological functioning of patients with cerebellar infarcts.
  • To evaluate the impact of lesion laterality on cognitive symptoms.
  • To assess cognitive recovery and return to work at 3 months post-infarction.

Main Methods:

  • Neuropsychological assessment of 26 patients with exclusive cerebellar lesions at acute stage and 3 months.

Related Experiment Videos

  • Comparison of patient performance with 14 healthy controls, assessed twice.
  • Focus on visuospatial/motor, episodic memory, working memory, and attentional/executive functions.

    • Main Results:

    • Both patients and controls improved over time.
    • Significant differences between groups were observed in visuomotor, episodic memory, and working memory domains.
    • Left cerebellar lesions were associated with visuospatial task slowness; right lesions with verbal memory difficulties.

    Conclusions:

    • Cerebellar infarcts can lead to subtle cognitive changes, potentially linked to working memory deficits.
    • Cognitive symptoms may be mediated by contralateral cortical hemisphere dysfunction.
    • Most patients (77%) returned to work within 3 months, indicating significant functional recovery.