Related Experiment Video
Updated: Aug 11, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Periocular microcystic adnexal carcinoma: management and outcome with Mohs' micrographic surgery
Igal Leibovitch1, Shyamala C Huilgol, Shawn Richards
1Oculoplastic and Orbital Unit, Department of Ophthalmology, Royal Adelaide Hospital, Adelaide, Australia.
Purpose:
To report a series of patients with periocular microcystic adnexal carcinoma (MAC) treated with Mohs' micrographic surgery (MMS).
Design:
Prospective, interventional case series.
Methods:
This series included all patients treated with MMS for periocular MAC, who were monitored by the Skin and Cancer Foundation Australia between 1993 and 2002.
Results:
There were 5 patients (4 males, 1 female) with a mean age of 52 +/- 12 years. Four tumors were located in the medial canthus and one in the lower lid. The tumor was initially misdiagnosed as basal cell carcinoma in 3 patients and squamous cell carcinoma in 1 patient. The average number of excision levels required for complete removal of the tumor during MMS was 2.2 (range 1-6). Perineural invasion was recorded in one patient.Five-year follow-up data was available for 3 patients, and there was no tumor recurrence in any of these cases.
Conclusion:
The low 5-year recurrence rate of periocular MAC with MMS emphasizes the importance of margin-controlled excision of this tumor.
