Related Experiment Videos
Possible sources of iron for lipid peroxidation
G Minotti1, M Di Gennaro, D D'Ugo
1Institute of General Pathology, Catholic University School of Medicine, Rome, Italy.
Free Radical Research Communications
|January 1, 1991
Abstract:
Possible sources of iron for lipid peroxidation are described and discussed. In particular, evidence is presented that microsomes contain ferric nonheme iron which may participate in formation of lipid oxidants, provided reductants are available to favor its mobilization from membrane binding sites. Aging- and tumor-associated changes of this microsomal pool of nonheme iron are also described and discussed from biochemical and biomedical viewpoints.