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Updated: Aug 11, 2026

The Power of Interstimulus Interval for the Assessment of Temporal Processing in Rodents
Published on: April 19, 2019
The level of prepulse inhibition in healthy individuals may index cortical modulation of early information processing
Stella G Giakoumaki1, Panos Bitsios, Sophia Frangou
1Department of Psychiatry and Behavioural Sciences, Medical School, University of Crete, Heraklion 71003, Crete, Greece.
Abstract:
This study examined whether baseline PPI levels reflect individual efficiency in tasks associated with routine versus supervisory attentional systems (SAS). PPI and neuropsychological data were collected from 30 healthy male subjects. High PPI was associated with shorter movement times on the 5-choice Reaction Time and shorter Subsequent Thinking Times in the Stockings of Cambridge test. These data suggest that high-PPI status reflects greater efficiency in tasks that engage SAS.

