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Complement, fetal antigen, and shaking rigors in parturients.
Michael D Benson1, Hiroshi Kobayashi, Lakshman R Sehgal
1Evanston Northwestern Healthcare, Evanston, Illinios, USA. benson.micheal@comcast.net
Summary
Complement levels drop slightly after childbirth but are not linked to fetal antigens or shaking rigors. Shaking rigors during labor show no association with these factors.
Area of Science:
- Immunology
- Obstetrics
- Perinatal Medicine
Background:
- Complement plays a role in immune responses.
- Fetal antigens are present during pregnancy.
- Shaking rigors can occur during labor and delivery.
Purpose of the Study:
- To investigate the relationship between complement levels, fetal antigen presence, and shaking rigors during labor and delivery.
- To determine if complement or fetal antigen levels correlate with the occurrence of shaking rigors.
Main Methods:
- Serial blood sampling was performed on 13 volunteers during labor and childbirth.
- Complement and fetal antigen levels were measured.
- The occurrence of shaking rigors was recorded.
Main Results:
- A small but significant decrease (11-15%) in complement levels was observed immediately postpartum.
- Complement levels showed no association with fetal antigen levels or shaking rigors.
- Fetal antigen levels did not demonstrate a consistent relationship with shaking rigors or the labor and delivery process.
Conclusions:
- Shaking rigors during labor and delivery are not associated with changes in complement or fetal antigen levels.
- Complement levels remain stable throughout labor, decreasing only after birth.
- Further research may explore other factors contributing to shaking rigors.