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Distribution of GABAA receptor subunit mRNAs in rat lumbar spinal cord
W Wisden1, A L Gundlach, E A Barnard
1ZMBH, Heidelberg, F.R.G.
Brain Research. Molecular Brain Research
|May 1, 1991
Abstract:
The expression of various GABAA receptor subunit mRNAs (alpha 1, alpha 2, alpha 3, alpha 5, beta 1, beta 2, beta 3, gamma 2, delta) was studied in the adult rat lumbar spinal cord by in situ hybridization. Of these, only alpha 2, alpha 3, beta 3 and gamma 2 mRNAs are expressed at significant levels. The alpha 3, beta 3 and gamma 2 transcripts are present in many neurons throughout the Rexed laminae, whereas the alpha 2 mRNA is restricted to motor neurons and adjacent cells.