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[Osteoporosis and digestive disease].

C Felly1, A Frei, O Lamy

  • 1Service de Gastro-enterologie et Hépatologie, Unité de maladies osseuses CHUV, 1011 Lausanne.

Revue Medicale Suisse
|February 24, 2006
PubMed
Summary

Patients on long-term cortisone therapy require calcium, vitamin D, and bisphosphonates to reduce fracture risk. Screening for celiac disease is recommended for idiopathic osteoporosis, and bisphosphonates are standard post-liver transplant.

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Area of Science:

  • Endocrinology
  • Gastroenterology
  • Orthopedics

Context:

  • Long-term cortisone use is associated with increased fracture risk.
  • Idiopathic osteoporosis requires investigation for underlying causes like celiac disease.
  • Hepatic transplantation necessitates specific post-operative management strategies.

Purpose:

  • To outline recommendations for managing fracture risk in patients on long-term cortisone therapy.
  • To emphasize the importance of screening for celiac disease in idiopathic osteoporosis.
  • To establish bisphosphonate administration as a standard protocol following hepatic transplantation.

Summary:

  • Patients receiving cortisone for over three months should be supplemented with calcium, vitamin D, and bisphosphonates to mitigate fracture risk.
  • Celiac disease screening is advised for all individuals diagnosed with idiopathic osteoporosis.
  • Bisphosphonate therapy should be routinely administered after hepatic transplantation.

Impact:

  • Improved patient outcomes through proactive fracture risk reduction.
  • Enhanced diagnosis of osteoporosis by identifying celiac disease as a contributing factor.
  • Standardized and effective post-transplant care protocols for liver recipients.

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