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Human metapneumovirus, Peru.

Gregory C Gray¹, Ana W Capuano, Sharon F Setterquist

¹University of Iowa College of Public Health, Iowa City, Iowa 52242, USA. gregory-gray@uiowa.edu

Emerging Infectious Diseases

|February 24, 2006

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Human metapneumovirus (HMPV) was detected in 2.3% of patients with influenzalike illness in Peru and Argentina between 2002-2003. Four of the six HMPV isolates belonged to the uncommon B1 genotype.

Area of Science:

Virology
Infectious Diseases
Epidemiology

Background:

Human metapneumovirus (HMPV) is a respiratory pathogen.
Influenzalike illness (ILI) is common, with various causative agents.
Understanding HMPV prevalence is crucial for public health.

Purpose of the Study:

To investigate the presence of HMPV in patients with ILI in Peru and Argentina.
To characterize the genotypes of detected HMPV strains.

Main Methods:

Retrospective analysis of 420 pharyngeal swab specimens.
Collected from Peruvian and Argentinean patients during 2002-2003.
Detection using multiple assays and isolation of HMPV.

Main Results:

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Twelve specimens (2.3%) tested positive for HMPV.
Six HMPV isolates were successfully obtained.
Four of these isolates were identified as the uncommon B1 genotype.

Conclusions:

HMPV circulates in South America among patients presenting with ILI.
The detection of the B1 genotype highlights potential geographic variations in HMPV strain prevalence.