Optical models for human myopic eyes
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Updated: Aug 11, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
1School of Optometry, Queensland University of Technology, Victoria Park Road, Kelvin Grove, Qld 4059, Australia. d.atchison@qut.edu.au
Abstract:
Data from the author's investigations and other studies are used to construct refractive dependent models. These models include a gradient index lens and aspheric corneal, lens and retinal surfaces. Elements that alter with refraction are anterior corneal radius, vitreous length and retinal shape (vertex radius of curvature and asphericity) and decentration. Two versions of the models are produced, one with centred and symmetrical optical elements, and one with tilts of the lens and decentrations and tilts of the retina. The centred model predicts increase in spherical aberration in myopia. It predicts the relative change in mean sphere in the periphery between the horizontal and vertical meridians that has been observed in a recent experimental study. It overestimates peripheral astigmatism by about 50%. The decentred version has limited success in predicting changes in peripheral refraction of average eyes.
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