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Published on: June 16, 2020
Disseminated Kikuchi-Fujimoto disease: a case report
Sondes Mseddi1, Salwa Makni, Moez Elloumi
1Hematology Department, Hédi Chaker Hospital Sfax, Tunisia. sondes.mseddi@rns.tn
Joint Bone Spine
|February 24, 2006
Summary
Kikuchi-Fujimoto disease, a benign condition, can mimic serious illnesses like lymphoma. This case highlights a young woman
Area of Science:
- Pathology
- Immunology
- Internal Medicine
Background:
- Subacute necrotizing lymphadenitis, or Kikuchi-Fujimoto disease (KFD), is a rare, benign condition.
- KFD primarily affects young adults and is characterized by lymphadenopathy and constitutional symptoms.
Observation:
- A 20-year-old woman presented with fever and significant cervical lymphadenopathy (up to 6 cm).
- Laboratory findings included elevated erythrocyte sedimentation rate (40 mm/h) and lactic dehydrogenase (593 IU/l).
- Extensive serological and tuberculosis testing yielded negative results.
Findings:
- Cervical lymph node biopsy revealed histopathological features of KFD, including nonsuppurative necrosis and histiocytic reaction.
- The patient experienced a complete recovery within 3 months without specific treatment.
Implications:
- KFD can present with symptoms mimicking hematological malignancies, such as lymphoma.
- Accurate diagnosis of KFD is crucial to avoid unnecessary aggressive treatments.
- This case underscores the importance of considering KFD in young adults with unexplained lymphadenopathy.
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