Gastric outlet obstruction due to giant hyperplastic gastric polyps

Hyperplastic gastric polyps account for the majority of benign gastric polyps. The vast majority of these lesions are small, asymptomatic, and found incidentally on radiologic or endoscopic examination. Giant hyperplastic gastric polyps are uncommon and most of them are asymptomatic. A 73-year-old man presented with a 6 cm pedunculated hyperplastic polyp that had led to progressive gastric outlet obstruction. It had a distinctive appearance on double-contrast barium studies, appearing as a conglomerate mass with smooth and multiple lobulated components and trapping of barium in the interstices between lobules. Endoscopy and computed tomography revealed similar features. Although hyperplastic gastric polyps are typically benign, total removal of this giant polyp should be undertaken in cases of symptomatic gastric outlet obstruction, followed by pathologic confirmation of benign nature.