Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Analysis and visualization of cell movement in the developing zebrafish brain.

Tobias Langenberg1, Tadeusz Dracz, Andrew C Oates

  • 1Biotechnology center, University of Technology, Dresden, Germany.

Developmental Dynamics : an Official Publication of the American Association of Anatomists
|February 24, 2006
PubMed
Summary

Researchers developed TracePilot, a novel software tool, to visualize and analyze embryonic cell movement in zebrafish. This aids in understanding complex tissue formation processes during vertebrate development.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Implementation of Integrated Behavioural Health in Outpatient Cardiology Care for Patients with Injection Drug Use-Associated Infective Endocarditis.

CJC open·2026
Same author

Multiple Notch ligands in the synchronization of the segmentation clock.

Physical review. E·2025
Same author

Unified mass imaging maps the lipidome of vertebrate development.

Nature methods·2025
Same author

Morphogen gradients are regulated by porous media characteristics of the developing tissue.

Development (Cambridge, England)·2025
Same author

Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain.

Developmental dynamics : an official publication of the American Association of Anatomists·2025
Same author

Fine-tuning of Fgf8 morphogen gradient by heparan sulfate proteoglycans in the extracellular matrix.

Biophysical journal·2024

Area of Science:

  • Developmental Biology
  • Computational Biology
  • Neuroscience

Background:

  • Understanding embryonic cell movement is crucial for tissue formation.
  • Analyzing large cell populations in vertebrates presents significant challenges.
  • Previous methods lacked efficient tools for spatiotemporal cell tracking.

Purpose of the Study:

  • To develop a software tool for interactive visualization and analysis of cell tracking data.
  • To facilitate the detailed reconstruction of embryonic cell spatiotemporal history.
  • To demonstrate novel visualizations of cell movement in the developing zebrafish brain.

Main Methods:

  • High-resolution time-lapse lineage tracing.
  • Antibody staining techniques.

Related Experiment Videos

  • Development of the Java-based TracePilot software for data analysis and visualization.

    • Main Results:

    • Successful analysis of mesencephalic and metencephalic cell population movements in early zebrafish embryos.
    • Demonstration of TracePilot's utility in generating novel visualizations of cell migration.
    • TracePilot enables interactive manipulation and exploration of complex cell tracking data.

    Conclusions:

    • TracePilot is a valuable, free, and extensible tool for analyzing embryonic cell movement.
    • The software aids in overcoming challenges associated with large-scale cell tracking in developmental studies.
    • Novel insights into zebrafish brain development can be gained through advanced visualization techniques.