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Published on: May 6, 2015
The rational design of an AIDS vaccine
Daniel C Douek1, Peter D Kwong, Gary J Nabel
1Vaccine Research Center, NIAID, National Institutes of Health, Room 4502, Building 40, MSC-3005, 40 Convent Drive, Bethesda, MD 20892, USA.
Abstract:
The extraordinary genetic diversity and immune evasion of human immunodeficiency virus (HIV) pose significant challenges for vaccine development. AIDS vaccine design requires a scientifically driven, rational approach that encompasses the latest advances in viral molecular genetics, structural biology, and immunology.
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