Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Skew deviation revisited.

Michael C Brodsky1, Sean P Donahue, Michael Vaphiades

  • 1Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. brodskymichaelc@uams.edu

Survey of Ophthalmology
|February 28, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Initial postoperative alignment versus long-term outcomes in intermittent exotropia surgery.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2026
Same author

Ocular motor atavisms: the evolutionary basis of infantile strabismus and nystagmus.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2026
Same author

The history and evolution of pediatric ophthalmology training: celebrating 50 years of the American Association for Pediatric Ophthalmology and Strabismus.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2026
Same author

Neuromyelitis Optica-Associated Acute Intermediate Uveitis.

International medical case reports journal·2025
Same author

Virtual reality perimetry facilitates visual field evaluation in a previously non-assessable eye with severe glaucoma.

American journal of ophthalmology case reports·2025
Same author

Defining and measuring population-level amblyopia treatment outcomes: a proposal by the AAPOS Vision Screening and Research Committees.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2025
Same journal

Trends in pediatric uveitis: A systematic review and meta-epidemiological investigation of geographic, economic, and climate factors.

Survey of ophthalmology·2026
Same journal

Efficacy and safety of different intraocular therapies for non-infectious uveitis: A network meta-analysis.

Survey of ophthalmology·2026
Same journal

Macular telangiectasia masqueraders.

Survey of ophthalmology·2026
Same journal

Utilization of anterior segment optical coherence tomography in childhood glaucoma: A systematic review.

Survey of ophthalmology·2026
Same journal

Peripapillary pachychoroid syndrome: Clinical and imaging features, diagnostic differentiation and therapeutic strategies.

Survey of ophthalmology·2026
Same journal

Prognostic factors and postoperative outcomes in pediatric cataract patients: A systematic review and meta-analysis.

Survey of ophthalmology·2026
See all related articles

Skew deviation, a vertical eye misalignment, results from vestibular system damage. This condition, often linked to brainstem or cerebellar injuries, presents with a specific set of ocular and head movements.

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Vestibular Science

Background:

  • Skew deviation is a vertical misalignment of the eyes.
  • It arises from damage to prenuclear vestibular input affecting ocular motor nuclei.
  • This condition is typically associated with brainstem or cerebellar injuries (stroke, MS, trauma).

Purpose of the Study:

  • To review the clinical localizing value of skew deviation.
  • To discuss the proposed vestibular mechanisms for skew deviation variants.
  • To explore the evolving understanding of skew deviation as central otolithic dysfunction.

Main Methods:

  • Review of clinical findings and proposed vestibular mechanisms.
  • Analysis of the ocular tilt reaction (skew deviation, torsion, torticollis, subjective visual vertical tilt).

Related Experiment Videos

  • Consideration of congenital strabismus in relation to skew deviation nosology.

    • Main Results:

    • Skew deviation is a relatively comitant vertical ocular deviation.
    • It is part of the ocular tilt reaction, including binocular torsion and head tilt.
    • Clinical localization and vestibular mechanisms for skew deviation have been established.

    Conclusions:

    • Skew deviation reflects central otolithic dysfunction in 3D space.
    • Understanding is evolving, potentially including vergence abnormalities in congenital strabismus.
    • Further research may expand the nosology of skew deviation.