Case report: endurance cycle ride associated with a significant rise in PSA

A number of disease processes are associated with an elevation in serum PSA. However, several studies have concluded that cycling is not an activity associated with an elevation in PSA. Herein, we summarise the literature and describe the case of a 54-year-old man who had presented to his General Practitioner (GP) with lower urinary tract symptoms 3 days after the completion of a 39-h endurance cycle ride. The PSA level was initially found to be elevated at 28 ng/ml, but decreased to 4 ng/ml and then 2 ng/ml within two and six months of the date of the cycle ride, respectively. It is probable that the elevation in PSA was caused by prolonged mechanical stimulation of the prostate during the cycle ride.