Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Psychological side effects during interferon-alpha therapy -- a case study].

Mathias Wölfelschneider1, Markus Schreiber, Sophia Holthausen-Markou

  • 1Klinik für Psychosomatische Medizin und Psychotherapie der Justus-Liebig-Universität Giessen.

Psychiatrische Praxis
|February 28, 2006
PubMed
Summary

Interferon-alpha (IFN-alpha) therapy can cause psychological side effects, often presenting as depression. Integrative psychosomatic psychotherapy can help manage these effects by addressing underlying psychosocial factors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular architecture of heterochromatin at the nuclear periphery of primary human cells.

Nature communications·2026
Same author

Update of the evidence- and consensus-based S3 guideline on atopic dermatitis: Systemic therapy with biologics or Janus kinase inhibitors and specific aspects of systemic therapy in pregnancy and lactation.

Allergologie select·2026
Same author

Atopic Dermatitis Across the Lifespan: Understanding, Measuring and Minimizing Cumulative Life Course Impairment.

Acta dermato-venereologica·2026
Same author

Context matters: A view on metadata analysis in cryo-electron tomography.

Current opinion in structural biology·2026
Same author

Position Statement of the EADV Task Forces With External Experts on Quality of Life Measurement in Hidradenitis Suppurativa: An Update.

International journal of dermatology·2026
Same author

S3 guideline diagnostics and therapy in alopecia areata - Part 2: Therapy, psychosocial and cosmetic support.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026

Area of Science:

  • Psychiatry
  • Hepatology
  • Psychosomatic Medicine

Background:

  • Interferon-alpha (IFN-alpha) is a common treatment for Hepatitis C, but its psychological side effects are a significant concern.
  • The exact pathways (somatopsychological vs. psychosomatic) mediating these effects remain poorly understood.

Observation:

  • A 26-year-old female patient with Hepatitis C developed agitation and somatization during IFN-alpha treatment.
  • Her condition necessitated transfer to a psychosomatic unit due to lack of response to psychotropic medications.

Findings:

  • Discontinuation of IFN-alpha led to emotional stabilization.
  • Psychotherapy addressed inner conflicts and medication-related fears.
  • Successful completion of IFN-alpha therapy was achieved with subsequent ambulatory psychotherapy.

Related Experiment Videos

Implications:

  • Integrative psychosomatic psychotherapy offers a supportive approach for managing IFN-alpha-induced psychological side effects.
  • Understanding psychosocial factors is crucial for optimizing IFN-alpha therapy outcomes.