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Updated: Aug 11, 2026
Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
[Cormobidity of sensorineural hearing loss and other autoimmune diseases. Usefulness of laboratory tests]
F J García Callejo1, J Corts, C de Paula Vernetta
1Servicio de Otorrinolaringología, Hospital Clínico Universitario de Valencia. jgarciacall@hotmail.com
Objectives:
To value if the sensorineural hearing loss (SHL) in several autoimmune diseases (AD) is also secondary to immunomediation.
Patients And Methods:
In 342 cases with SHL and any AD and 301 normoacoustic controls with AD a non-specific immunologic battery of tests and a Western-blot (WB) for anticochlear autoantibodies were developed, and cases with SHL were treated with deflazacort.
Results:
Alterations in non-specific battery were similar between cases and controls. But a 12,5% of cases with SHL and a 1,6% of normoacoustic showed a positive WB (p<0,001). Steroid therapy improved hearing in 14,3% of cases. In them, sensitivity and specificity of non-specific battery were 78,4% and 75,5%, respectively, to predict response to therapy. These were 98,9% and 81,6% for WB.
Conclusions:
The SHL in cases with AD can be considered immunomediated in a discrete average, but the diagnostic efficiency of WB to predict an improvement after steroid therapy is high.
