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Published on: June 4, 2017
Prevalence of chronic rheumatic heart disease in Chinese adults
Wang Zhimin1, Zou Yubao, Song Lei
1Department of Echocardiography, Fu wai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, Beijing 100037, PR China.
Insights
Rheumatic heart disease affects approximately 2 million Chinese adults, highlighting a significant public health burden. This study assessed chronic rheumatic heart disease prevalence in China using echocardiography.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Rheumatic heart disease (RHD) remains prevalent in developing nations.
- Previous data on RHD prevalence in China is outdated, necessitating current assessment.
- Understanding RHD's current impact is crucial for public health strategies.
Purpose of the Study:
- To determine the current prevalence of chronic rheumatic heart disease in China.
- To provide objective data on RHD burden in the Chinese population.
- To inform future interventions and resource allocation for RHD management.
Main Methods:
- A community-based, multistage random sampling investigation was conducted across nine Chinese provinces.
- Echocardiographic imaging, including mitral valve views and color flow Doppler, was used for RHD diagnosis.
- M-mode and 2D echocardiography assessed the aortic root and left atrium to support diagnoses.
Main Results:
- Out of 8080 participants who underwent echocardiography, 15 individuals showed definitive evidence of RHD.
- The estimated prevalence of RHD was 186 per 100,000 adults, equivalent to 2 in 1000.
- This prevalence suggests approximately 2 million middle-aged to elderly Chinese are affected.
Conclusions:
- Rheumatic heart disease represents a substantial health burden affecting millions in China.
- The study's focus on urban and suburban areas may lead to an underestimation of the true national prevalence.
- Further research including rural populations is recommended to ascertain the complete RHD burden.
Objectives:
Rheumatic heart disease continues to be a common health problem in the developing countries. Though there is evidence indicating that rheumatic heart disease prevalence in China has decreased since the 1950s, no objective assessment of its present prevalence has been published. The study was designed to investigate the prevalence of chronic rheumatic heart disease in China.
Methods:
We performed a community population based investigation from October 2001 to February 2002 in nine communities of nine provinces in China by using a multistage, random sample design. Rheumatic heart disease was diagnosed by echocardiographic imaging. Long-axis views of the mitral valve, color flow recordings were used to search for mitral and aortic regurgitations. M-mode and two-dimensional short- and long-axis views of the aortic root and left atrium were recorded for supporting the diagnosis.
Results:
Of 9124 participants, 8652 completed the questionnaires and 8080 had comprehensive echocardiographic examinations. We found that 15 subjects had definite echocardiographic evidence of rheumatic heart disease. The rough prevalence of rheumatic heart disease was 186/100,000 adults (2 in 1000 adults).
Conclusions:
Rheumatic heart disease affected approximately 2 million middle-aged to elderly Chinese, thus constituting a significant health burden. We investigated only urban and suburban communities, the result may underestimate the real prevalence of the disease in China.
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