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Related Experiment Videos

[Antimicrobial therapy in dermatology].

Cord Sunderkötter1, Mathias Herrmann, Uta Jappe

  • 1Department of Dermatology and Allergology, University Clinic of Ulm; and Department of Dermatology and Venerology, University Hospital Münster, Germany. cord.sunderkoetter@ukmuenster.de

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
|March 1, 2006
PubMed
Summary

Antibiotic overuse in skin infections fuels resistance. This review advocates for rational antibiotic use in dermatology, prioritizing topical antiseptics and specific beta-lactam antibiotics for common bacterial infections.

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Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis - a monocentric, retrospective, explorative study.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Pharmacology

Context:

  • Extensive and indiscriminate antibiotic use has increased bacterial resistance and patient sensitization.
  • Systemic antibiotics are indicated for severe or spreading skin infections, especially in patients with diabetes, immunosuppression, or peripheral arterial occlusive disease.
  • Topical antibiotic use should be replaced by antiseptics.

Purpose:

  • To define antibiotic indications in dermatology.
  • To highlight antibiotic mechanisms of action and adverse effects.
  • To provide guidance for rational antibiotic therapy in common cutaneous infections.

Summary:

  • Beta-lactam antibiotics are often first-line for skin infections due to efficacy, safety, and affordability.

Related Experiment Videos

  • Penicillin G or V for erysipelas; isoxazolyl penicillins or cephalosporins for Staphylococcus aureus.
  • Mixed infections in high-risk patients may require metronidazole plus beta-lactam/beta-lactamase inhibitors, quinolones, or cephalosporins.

    • Impact:

    • Promotes judicious antibiotic selection to combat resistance.
    • Improves patient outcomes by ensuring appropriate treatment for skin infections.
    • Reduces adverse drug events and healthcare costs associated with antibiotic misuse.