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Updated: Jul 16, 2026

Functional Calcium Imaging in Developing Cortical Networks
Published on: October 22, 2011
Calcium and NeuroD2 control the development of thalamocortical communication
1Department of Physiology, Anatomy and Genetics, Le Gros Clark Building, University of Oxford, Oxford, OX1 3QX, United Kingdom.
Abstract:
Donald Hebb postulated the existence of a mechanism of activity-dependent transcription and synaptic modification almost 60 years ago. While the details of this process are still unclear, a new study by Ince-Dunn et al. in this issue of Neuron indicates that NeuroD2, a calcium-regulated transcription factor, plays a central role in thalamocortical synaptic maturation.
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