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Updated: Aug 11, 2026

Assessment of de novo Protein Synthesis Rates in Caenorhabditis elegans
Published on: September 12, 2020
Rookie snail protein LAPS veteran C/EBP: net transcriptional proceeds for long-term facilitation
Kristin L Eckel-Mahan1, Daniel R Storm
1Department of Pharmacology, University of Washington, Seattle, Washington 98195, USA.
Abstract:
Long-term changes in synaptic plasticity require new protein synthesis. This preview discusses data from Kim et al. (this issues of Neuron) that demonstrate the requirement of a novel, nucleolar protein, LLP (LAPS18-like protein), for the formation of long-term facilitation in Aplysia. LLP binds to and transcriptionally activates C/EBP, thereby promoting the formation of long-term facilitation and behavioral sensitization.
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