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Related Experiment Videos

Weight-supported treadmill vs over-ground training for walking after acute incomplete SCI.

B Dobkin1, D Apple, H Barbeau

  • 1Department of Neurology, University of California Los Angeles, Neurologic Rehabilitation and Research Program, Reed Neurologic Research Center, Los Angeles, CA 90095, USA. bdobkin@mednet.ucla.edu

Neurology
|March 1, 2006
PubMed
Summary

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Body weight support on a treadmill and over-ground mobility therapy showed similar efficacy for incomplete spinal cord injury patients. Both rehabilitation strategies yielded comparable improvements in walking function for individuals with varying degrees of spinal cord injury.

Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Clinical Trials

Background:

  • Incomplete spinal cord injury (SCI) presents significant challenges to mobility and functional independence.
  • Rehabilitation strategies aim to maximize recovery and improve walking ability in SCI patients.
  • Comparing different therapeutic approaches is crucial for optimizing patient outcomes.

Purpose of the Study:

  • To compare the efficacy of body weight support on a treadmill (BWSTT) with over-ground practice against conventional over-ground mobility therapy (CONT).
  • To evaluate functional outcomes in patients with incomplete SCI undergoing inpatient rehabilitation.

Main Methods:

  • A multicenter, single-blinded, randomized clinical trial (MRCT) involving 146 subjects with incomplete SCI (ASIA B, C, D; C5-L3 levels; FIM-L score < 4).

Related Experiment Videos

  • Participants received 12 weeks of either BWSTT or CONT.
  • Primary outcomes assessed at 6 months post-SCI included Functional Independence Measure for locomotion (FIM-L) and walking speed.

    • Main Results:

    • No significant differences were observed between BWSTT and CONT groups in FIM-L scores or walking speed/distance at 6 months.
    • A high percentage of upper motor neuron (UMN) subjects achieved independent walking: 35% of ASIA B, 92% of ASIA C, and 100% of ASIA D.
    • Walking velocities were comparable between BWSTT and CONT for ASIA C and D UMN subjects.

    Conclusions:

    • BWSTT and conventional over-ground mobility therapy demonstrate similar efficacy in improving walking function for incomplete SCI patients.
    • The high rate of functional walking in ASIA C subjects, regardless of treatment, highlights the potential for recovery in this population.
    • This study underscores the value of MRCTs in evaluating rehabilitation strategies and provides insights into disability after incomplete SCI.