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Published on: October 20, 2017
Systemic septic embolisation secondary to an atrial myxoma in a young woman
Alice M Veitch1, Nathan E Manghat, Nirmal K Kakani
1Department of Clinical Radiology, Derriford Hospital, Plymouth, PL6 8DH, UK. amveitch@doctors.org.uk
Abstract:
We present a case of a left atrial myxoma infected with Staphylococcus aureus in a 35-year-old woman who was found to have a retained tampon. Multiple systemic septic emboli were seen on computed tomography imaging of the brain, spleen and kidneys. She was successfully treated by surgical excision of the myxoma and 4 weeks of antibiotic therapy. We postulate that the source of this patient's S. aureus infection was tampon use, leading to a toxic shock syndrome and causing infection of an undiagnosed left atrial myxoma, which led to the embolisation. As far as the authors are aware, this is the first reported case of such an entity. In those with an underlying cardiac predisposition, tampon use may represent a risk of infection with S. aureus, and we intend to heighten clinical awareness of this potentially life-threatening association. We also discuss the diagnosis, complications and treatment of infected atrial myxoma and illustrate the imaging findings.
Insights
This case report details a rare instance of a left atrial myxoma infected by Staphylococcus aureus, potentially linked to tampon use and toxic shock syndrome. Prompt surgical removal and antibiotics led to successful patient recovery.
Area of Science:
- Cardiology
- Infectious Diseases
- Toxicology
Background:
- Atrial myxomas are rare primary cardiac tumors, typically benign.
- Staphylococcus aureus is a common pathogen, capable of causing severe infections.
- Toxic shock syndrome (TSS) is a severe, life-threatening condition caused by bacterial toxins.
Observation:
- A 35-year-old woman presented with systemic septic emboli secondary to an infected left atrial myxoma.
- Computed tomography revealed emboli in the brain, spleen, and kidneys.
- The patient had a history of retained tampon use, suggesting a potential source of Staphylococcus aureus infection.
Findings:
- The left atrial myxoma was infected with Staphylococcus aureus, leading to TSS and subsequent septic embolization.
- Surgical excision of the myxoma combined with a 4-week course of antibiotics resulted in a full recovery.
- This represents the first reported case of a left atrial myxoma infected by Staphylococcus aureus secondary to tampon use and TSS.
Implications:
- Tampon use may pose a risk for Staphylococcus aureus infection in individuals with undiagnosed cardiac conditions like atrial myxoma.
- Heightened clinical awareness is crucial for recognizing this potentially life-threatening association.
- The case underscores the importance of considering infectious etiologies in cardiac tumors and highlights diagnostic and therapeutic strategies for infected atrial myxoma.
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