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Abstract:
Fifty-seven episodes of pulmonary infection occurred in 46 patients during a 11.5-year period, the incidence being 12% (57/475). After treatment, 22 patients recovered, and 24 died (52%). The etiology was determined in 47 infection episodes. 38(81%) of them were caused by bacteria, 6 by fungi, and 3 by tubercle bacilli. Comparisons were made between infected and noninfected groups. The results showed that the incidence of rejection episodes, greatly elevated blood sugar level (greater than or equal to 11.1 mmol/L) and granulocytopenia (less than or equal to 1.5 10(9)/L) influenced significantly the morbidity and mortality of pulmonary infection.
Insights
Pulmonary infections in patients led to significant mortality. Key risk factors included transplant rejection, high blood sugar, and low white blood cell counts, impacting patient outcomes.
Area of Science:
- Medicine
- Infectious Diseases
- Pulmonology
Background:
- Pulmonary infections pose a significant threat in clinical settings.
- Understanding risk factors is crucial for improving patient outcomes.
Purpose of the Study:
- To investigate the incidence, etiology, and risk factors associated with pulmonary infections.
- To determine the impact of specific clinical conditions on pulmonary infection morbidity and mortality.
Main Methods:
- Retrospective analysis of 475 patients over 11.5 years.
- Identification and categorization of pulmonary infection episodes and their causes.
- Comparative analysis between infected and non-infected patient groups.
Main Results:
- Pulmonary infections occurred in 12% of patients, with a 52% mortality rate.
- Bacterial pathogens were the most common cause (81%), followed by fungi and tubercle bacilli.
- Transplant rejection episodes, hyperglycemia (≥11.1 mmol/L), and granulocytopenia (≤1.5 10(9)/L) were significant predictors of morbidity and mortality.
Conclusions:
- Pulmonary infections are associated with high mortality.
- Elevated blood sugar and granulocytopenia are critical risk factors influencing outcomes.
- Proactive management of these conditions may reduce pulmonary infection-related deaths.