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Updated: Aug 11, 2026
Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
Preoperative autologous blood donation in primary total knee arthroplasty: a single-centre experience on 214
M Franchini1, D Regis, G Gandini
1Servizio di Immunoematologia e Trasfusione, Azienda Ospedaliera di Verona, Verona, Italy. massimo.franchini@mail.azosp.vr.it
Background And Objectives:
Although preoperative autologous blood donation (PABD) is a widespread practice in elective orthopedic surgery, it is controversial whether this procedure avoids allogeneic blood transfusions in patients undergoing total knee arthroplasty (TKA).
Patients And Methods:
We performed a retrospective study on 214 consecutive patients undergoing PABD before elective primary TKA.
Results:
Thirty-eight patients (17.8%) were transfused with autologous red blood cells (RBC), while four of them (10.5% of those requiring transfusions, 1.9% of all patients) also received allogeneic RBC. The transfused patients were, in most cases, female and had significantly lower basal and preoperative haemoglobin levels.
Conclusions:
Based on the results of this study, PABD is not necessary in most patients undergoing TKA, although older female patients with low basal haemoglobin levels could benefit from a predeposit programme and/or erythropoietin support in order to reduce the risk of exposure to allogeneic blood.
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