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Published on: July 5, 2011
Neurologic complications of cardiac surgery: current concepts and recent advances
1Department of Neurology, Mt. Sinai School of Medicine, New York, NY 10028, USA. DJB928@aol.com
Insights
Neurologic complications after cardiac surgery, including stroke and cognitive deficits, pose risks. Mechanical clot retrievers and novel approaches may improve outcomes for these serious conditions.
Area of Science:
- Neurology
- Cardiology
- Neurosurgery
Background:
- Neurologic complications increase morbidity and mortality after cardiac surgery.
- Stroke incidence is 2-4%, higher in patients with prior stroke history.
- Off-pump techniques and combined carotid endarterectomy/coronary artery bypass surgery risks are debated.
Purpose of the Study:
- To review neurologic complications following cardiac surgery.
- To discuss the efficacy and safety of various surgical techniques and emerging treatments.
- To explore the causes and management of postoperative stroke, cognitive deficits, and seizures.
Main Methods:
- Literature review of neurologic complications in cardiac surgery patients.
- Analysis of stroke incidence, risk factors, and treatment options.
- Discussion of neurocognitive dysfunction and seizure etiologies and management.
Main Results:
- Mechanical clot retrievers show promise for treating large middle cerebral artery strokes.
- Cognitive deficits may not be solely due to bypass and often resolve within 1-3 months.
- Postoperative seizures stem from ischemia, emboli, or metabolic issues, with new anticonvulsants offering management.
Conclusions:
- Neurologic complications are significant concerns after cardiac surgery.
- Emerging technologies and approaches may mitigate risks and improve patient outcomes.
- Further research is needed to clarify long-term risks and optimize neuroprotection strategies.
Abstract:
Neurologic complications following cardiac surgery result in increased morbidity and mortality. The incidence of stroke is 2% to 4%, but is substantially higher in patients with a prior history of stroke. The success of off-pump techniques in altering this risk is controversial. The efficacy and safety of simultaneous carotid endarterectomy and coronary artery bypass surgery are still debated. Mechanical clot retrievers may offer new opportunity to treat postoperative large, middle cerebral artery strokes. The risk of cognitive deficits is debatable but may be due to factors other than the use of bypass and may not differ from similar deficits after noncardiac surgery. Short-term cognitive deficits usually resolve by 1 to 3 months. Long-term risks are not clearly established. Novel approaches may decrease the incidence of neurocognitive dysfunction. Postoperative seizures may result from global or focal cerebral ischemia due to hypoperfusion, particulate or air emboli, or metabolic causes. Newer anticonvulsant drugs may offer additional management opportunities.
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