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Updated: Aug 11, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Maternal psychological morbidity and low birth weight in India
1NPHIRU, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. Vikram.patel@lshtm.ac.uk
Abstract:
Depression following childbirth is associated with poor child growth in developing countries. We describe the association between psychological morbidity during pregnancy and low birth weight (<2.5 kg). A cohort of 270 mothers was recruited from a district hospital in Goa, India; all mothers were interviewed with a screening questionnaire for psychological morbidity. Babies of 250 mothers were reviewed at birth to measure their weight. Excluding 5 premature babies, we found that maternal psychological morbidity was independently associated with low birth weight (odds ratio 1.44, 95% CI 1.0-2.07). We conclude that maternal psychological morbidity has an adverse impact on foetal growth.
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