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Determination of phenytoin sodium injection and tablets by highly accurate nephelometric titration
Tao Yi1, Xian-Cheng Zhan, Cheng-Rong Li
1West China School of Pharmacy, Sichuan University, Chengdu, People's Republic of China.
Abstract:
A highly accurate nephelometric titration method was developed for the quantitative analysis of phenytoin sodium injection and tablets. The titration operating conditions and the validation of the method were studied. Five batches of phenytoin sodium injection and tablets were determined by the proposed method and the control experiment methods, respectively. The results of the titration are comparable to those of control experiments. The proposed method is accurate and reproducible, which is considered suitable for the quantitative analysis of a large number of samples.
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