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Kikuchi disease in Asian children
Ching K Chen1, Yee Low, Meenakshi Akhilesh
1Department of Paediatric Surgery, KK Women's and Children's Hospital, Singapore, Singapore.
Journal of Paediatrics and Child Health
|March 3, 2006
Summary
Kikuchi disease, a rare condition in children, often presents with fever and cervical lymphadenopathy. This study highlights its features in pediatric patients, suggesting it’s more common than previously thought.
Area of Science:
- Pediatric Medicine
- Immunology
- Pathology
Background:
- Kikuchi disease is a rare, benign, self-limiting condition typically affecting adults.
- Paediatric cases of Kikuchi disease are infrequently reported.
- This study aims to describe Kikuchi disease features in children and increase clinical awareness.
Observation:
- A retrospective review of nine paediatric cases of Kikuchi disease was conducted.
- Patients aged 7–16 years presented with fever and cervical lymphadenopathy.
- Histological findings confirmed the diagnosis in all cases.
Findings:
- All nine paediatric patients exhibited fever and cervical lymphadenopathy.
- Elevated erythrocyte sedimentation rate was noted, with no other significant laboratory abnormalities.
- Hepatosplenomegaly was observed in one patient.
Implications:
- Kikuchi disease may be more common in children than previously recognized.
- Consider Kikuchi disease in the differential diagnosis for paediatric fever of unknown origin or cervical lymphadenopathy.
- Early diagnosis can prevent unnecessary investigations and prolonged treatments.