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Published on: September 11, 2011
Cumulative effective doses delivered by radiographs to preterm infants in a neonatal intensive care unit
Jean Donadieu1, Abdelkrim Zeghnoun, Candice Roudier
1Département Santé et Environnement, Institut de Veille Sanitaire, St Maurice, France. j.donadieu@invs.sante.fr
Insights
Preterm infants in the NICU received a median of 10.6 radiographs, totaling 138 microSv. These cumulative effective doses (cED) appear low, but further research is needed on long-term effects.
Area of Science:
- Medical Imaging
- Pediatric Radiology
- Neonatal Intensive Care
Background:
- Preterm infants (PIs) often require frequent radiographic imaging in the NICU.
- Assessing cumulative effective radiograph doses (cED) is crucial for understanding radiation exposure in this vulnerable population.
Purpose of the Study:
- To quantify the number and distribution of radiographs and cED in hospitalized preterm infants.
- To identify factors influencing cED in preterm infants.
Main Methods:
- Retrospective review of 450 preterm infant (gestational age <34 weeks) files admitted to an NICU over 18 months.
- Generalized additive models were used to analyze the relationship between cED and patient characteristics.
Main Results:
- Median radiographs per infant: 10.6 (range: 0-95); median cED: 138 microSv (range: 0-1450 microSv).
- 7.6% of infants exceeded 500 microSv cumulative dose.
- Gestational age, birth weight, care procedures, and clinical adverse events influenced cED.
Conclusions:
- Cumulative radiograph doses in the NICU appear low relative to international recommendations for preterm infants.
- Further studies are necessary to evaluate the long-term consequences of early-life ionizing radiation exposure.
Objective:
We sought to determine the number and distribution of radiographs and the cumulative effective radiograph doses (cED) received by a population of preterm infants (PIs) hospitalized in an NICU.
Study Design:
We reviewed the files of all preterm infants (gestational age: <34 weeks) who were admitted to an NICU during an 18-month period and were discharged alive. A generalized additive model was used to study the relationship between cED and patient characteristics.
Results:
Four hundred fifty files were analyzed. The median gestational age was 30.1 weeks (range: 24.1-33.9 weeks), and the median birth weight was 1250 g (range: 520-2760 g). The median number of radiographs per infant was 10.6 (range: 0-95), and the median cED was 138 microSv (range: 0-1450 microSv). The cumulative dose exceeded 500 microSv in 7.6% of the cases. Factors that influenced the cumulative effective dose were gestational age, birth weight, care procedures, and clinical adverse events.
Conclusions:
Given the potentially life-threatening complications of PIs, cumulative radiograph doses received in the ICU seem low with regard to environmental exposure and international recommendations. Additional studies are needed to evaluate the possible lifetime consequences of exposure to ionizing radiation at this age.
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