Epileptic nystagmus: two case reports, clinical and pathophysiological review of the literature
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Updated: Aug 11, 2026

Simultaneous Eye Tracking and Single-Neuron Recordings in Human Epilepsy Patients
Published on: June 17, 2019
Yvonne G Weber1, Johannes Roesche, Holger Lerche
1Department of Neurology, University of Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany.
Abstract:
Epileptic nystagmus (EN) is characterized by repetitive eye movements as a symptom of seizure activity. Two cases of EN are reported including ictal EEG, video recordings and MRI. In addition, we review the published cases and pathophysiological background of EN. The cardinal cortical region for EN is located at the junction of Brodmann areas 19/37/39 correlating with the main epileptogenic region observed in the analyzed cases.
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