Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Multiple cerebral de novo aneurysms.

H A van Alphen¹, G Yong-Zhong

¹Department of Neurosurgery, Free University Hospital, Amsterdam, The Netherlands.

Clinical Neurology and Neurosurgery

|January 1, 1991

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Elective trepanation for acute epidural hematoma by Dr. Nicolaes Tulp (1593-1674).

Neurosurgery·2001

Same author

Comparative double blind clinical trial of phenytoin and sodium valproate as anticonvulsant prophylaxis after craniotomy: efficacy, tolerability, and cognitive effects.

Journal of neurology, neurosurgery, and psychiatry·1999

Same author

Clinical assessment of a novel antiadhesion barrier gel: prospective, randomized, multicenter, clinical trial of ADCON-L to inhibit postoperative peridural fibrosis and related symptoms after lumbar discectomy.

American journal of orthopedics (Belle Mead, N.J.)·1998

Same author

Morphology of the human internal vertebral venous plexus: a cadaver study after intravenous Araldite CY 221 injection.

The Anatomical record·1997

Same author

Operative treatment of spontaneous spinal epidural hematomas: a study of the factors determining postoperative outcome.

Neurosurgery·1996

Same author

Hypofractionated radiation therapy in patients with glioblastoma multiforme: results of treatment and impact of prognostic factors.

International journal of radiation oncology, biology, physics·1996

Two female patients developed new cerebral mirror aneurysms years after prior surgery. This suggests an inborn vessel wall weakness contributes to aneurysm formation, alongside acquired factors and blood flow dynamics.

Area of Science:

Neurology
Vascular Surgery
Medical Imaging

Background:

Cerebral aneurysms are a significant cause of subarachnoid hemorrhage.
Previous surgical treatment for intracranial aneurysms is a known risk factor for recurrence or new aneurysm formation.
The development of mirror aneurysms, appearing bilaterally or symmetrically, suggests underlying systemic factors.

Observation:

Two female patients previously treated for a midline cerebral aneurysm developed new, distinct mirror aneurysms years later.
These new aneurysms appeared in a mirrored location relative to the initial aneurysm.
Detailed imaging and clinical follow-up were performed.

Findings:

The occurrence of new mirror aneurysms suggests a predisposition or inherent weakness in the cerebral vasculature.

Related Experiment Videos

Both congenital (inborn vessel wall weakness) and acquired factors (e.g., surgical intervention, hemodynamic stress) likely contribute to aneurysm genesis.

The findings highlight the complex etiology of cerebral aneurysms.

Implications:

Understanding the role of inherent vessel wall susceptibility is crucial for predicting aneurysm risk.
This case series emphasizes the need for long-term surveillance in patients with a history of cerebral aneurysms.
Further research into the genetic and environmental factors influencing cerebral aneurysm development is warranted.