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Related Experiment Videos

Melioidosis in imported non-human primates.

A F Kaufmann1, A D Alexander, M A Allen

  • 1Epidemiology Program, National Communicable Disease Center, HSMHA, PHS, USDHEW, Atlanta, Georgia 30333, USA.

Journal of Wildlife Diseases
|October 1, 1970
PubMed
Summary

Five nonhuman primates in the US were diagnosed with melioidosis in 1969. These cases marked the first known instances of spontaneous melioidosis in these animals in the United States.

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Area of Science:

  • Veterinary Pathology
  • Primate Medicine
  • Infectious Diseases

Background:

  • Melioidosis is a bacterial infection caused by Burkholderia pseudomallei.
  • It is endemic in Southeast Asia and Australia, but rare in the United States.
  • Nonhuman primates are susceptible to various infectious diseases, posing risks in research and zoological settings.

Observation:

  • In 1969, five cases of melioidosis were diagnosed in three separate outbreaks in US-housed nonhuman primates.
  • Two stump-tailed macaques (Macaca arctoides) developed melioidosis 6 months post-purchase; a chimpanzee (Pan troglodytes) likely contracted it from them.
  • Two additional unrelated cases involved a pig-tailed macaque (Macaca nemestrina) and a rhesus macaque (Macaca mulatta), imported years earlier.

Findings:

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  • These five cases represent the first documented occurrences of spontaneous melioidosis in nonhuman primates within the United States.
  • The disease manifested in animals with varying import histories, suggesting potential environmental or transmission factors.
  • Diagnosis involved clinical signs and likely laboratory confirmation, though details are not specified.
  • Implications:

    • Highlights the potential for exotic diseases to emerge in naive animal populations.
    • Underscores the importance of rigorous import health screening for nonhuman primates.
    • Informs veterinary surveillance and diagnostic strategies for melioidosis in captive primates in non-endemic regions.