Related Experiment Video
Updated: Aug 11, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
[The specific features of coronary heart disease in patients with pulmonary tuberculosis]
Insights
Coronary heart disease (CHD) affects 8.4% of pulmonary tuberculosis patients, particularly elderly females. Clinical signs of CHD are more common in those with less active or residual tuberculosis.
Area of Science:
- Cardiology
- Pulmonology
- Epidemiology
Context:
- Pulmonary tuberculosis (TB) is a significant global health issue.
- Comorbidities like coronary heart disease (CHD) can complicate TB management.
- Understanding the interplay between TB and CHD is crucial for patient care.
Purpose:
- To investigate the prevalence and specific characteristics of coronary heart disease (CHD) in patients diagnosed with pulmonary tuberculosis.
- To analyze the relationship between CHD prevalence and factors such as age, gender, and the nature of the tuberculous process.
- To identify potential indicators of CHD in pulmonary tuberculosis patients, including electrocardiogram (ECG) changes.
Summary:
- Coronary heart disease (CHD) was diagnosed in 8.4% (41 of 491) of patients with pulmonary tuberculosis.
- CHD prevalence was higher in elderly and senile females. Clinical manifestations appeared at older ages in females compared to males.
- Above 60 years, CHD prevalence in TB patients matched the general population. Less active or residual TB correlated with more frequent CHD clinical signs.
Impact:
- This study highlights the increased risk of CHD in pulmonary tuberculosis patients, especially older females.
- Findings suggest that ECG changes may indicate CHD even without prior diagnosis in TB patients.
- Identifying CHD in TB patients can lead to timely interventions, improving patient outcomes and reducing comorbidity burden.
Abstract:
The prevalence and some specific features of coronary heart disease (CHD) were studied in patients with pulmonary tuberculosis. Its prevalence was determined in relation to age, gender, and the type of a tuberculous process. ECG changes in ST segment and T wave were found in patients with pulmonary tuberculosis without concomitant CHD under intoxication. The diagnosis of CHD was established in 41 of 491 patients, which was 8.4%. CHD was more common in elderly and senile females. The clinical manifestation of CHD was observed in females of older age than in males; under the age of 60 years, the prevalence of CHD is less among the patients with pulmonary tuberculosis and above the age of 60 years, it does not differ from that in the general population. CHD most commonly manifests clinical signs in patients with residual changes after experienced pulmonary tuberculosis and in cirrhotic tuberculosis, i.e. when the tuberculosis process is less active.
Related Concept Videos
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Other Pulmonary Disorders
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...