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Monoclonal antibodies to Kunjin and Kokobera viruses
R A Hall1, G W Burgess, B H Kay
1Queensland Institute of Medical Research, Herston, Australia.
Immunology and Cell Biology
|February 1, 1991
Abstract:
Five monoclonal antibodies (MoAb) were produced to the envelope (E) protein of Kunjin (KUN) virus. Three of these were specific for the KUN/West Nile complex, and two reacted with epitopes that were common to the flavivirus family. These MoAb defined at least four distinct epitopes on the E protein of KUN virus. Eight MoAb were also produced to unidentified proteins of Kokobera (KOK) virus. Seven were specific for KOK, while the remaining antibody cross-reacted with Stratford virus and an unregistered flavivirus CS946. The application of these MoAb to arboviral surveillance is discussed.