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Related Experiment Videos

Gender and peripheral arterial disease.

Tracie C Collins1, Maria Suarez-Almazor, Ruth L Bush

  • 1Houston Center for Quality of Care and Utilization Studies, Michael E. DeBakey Veterans Affairs Medical Center, and Section of Health Services Research, Baylor College of Medicine, Houston, TX 77030, USA. tcollins@bcm.tmc.edu

Journal of the American Board of Family Medicine : JABFM
|March 4, 2006
PubMed
Summary

Peripheral arterial disease (PAD) prevalence does not differ by gender, but women with PAD experience greater walking impairment and reduced quality of life. Further research is needed to improve limb function in these patients.

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Area of Science:

  • Cardiovascular Medicine
  • Vascular Health
  • Epidemiology

Background:

  • Peripheral arterial disease (PAD) affects a significant number of patients in primary care settings.
  • Understanding gender-specific differences in PAD risk factors and symptoms is crucial for targeted interventions.
  • Previous research has not fully elucidated the nuances of PAD presentation between genders.

Purpose of the Study:

  • To investigate gender disparities in the risk factor profile of peripheral arterial disease (PAD).
  • To compare leg symptoms and functional outcomes in men and women diagnosed with PAD.
  • To assess the impact of PAD on quality of life across different genders.

Main Methods:

  • A cohort of 403 patients aged 50 and older diagnosed with PAD via ankle-brachial index (ABI) < 0.9 was analyzed.

Related Experiment Videos

  • Patients completed validated questionnaires assessing leg symptoms (San Diego Claudication Questionnaire), walking impairment, and health-related quality of life.
  • Data were stratified by race and gender to identify demographic and clinical differences.

    • Main Results:

    • PAD prevalence did not significantly differ between genders, though variations were noted across racial groups within women.
    • Identical risk factors (diabetes, smoking, hypertension medication) were observed for men and women with PAD.
    • Women with PAD reported lower scores for walking impairment, physical function, and general health compared to men with PAD.

    Conclusions:

    • PAD prevalence is consistent across genders in primary care, challenging previous assumptions.
    • Women diagnosed with PAD face a higher risk of compromised daily function and diminished quality of life.
    • Future research should focus on developing strategies to prevent walking impairment and enhance limb function, especially for women with PAD.