Pharmacogenetics: development issues and solutions for safe and effective medicines

Corrigendum to 'Intradiscal linezolid (PP353) treatment for chronic low back pain associated with Modic change type 1: an international, first-in-human, randomised, sham procedure-controlled, double-blind, phase 1b clinical trial' eClinicalMedicine 2026; 92: 103764.

EClinicalMedicine·2026

Intradiscal linezolid (PP353) treatment for chronic low back pain associated with Modic change type 1: an international, first-in-human, randomised, sham procedure-controlled, double-blind, phase 1b clinical trial.

EClinicalMedicine·2026

Phase 1/2, open-label study of oral bacterial supplementation (EDP1503) plus pembrolizumab in participants with advanced or metastatic microsatellite-stable colorectal cancer, triple-negative breast cancer, and checkpoint inhibitor-relapsed tumors.

Investigational new drugs·2025

Pharmacokinetics of PP353, a formulation of linezolid for intervertebral disc administration, in patients with chronic low back pain and Modic change Type 1: A first-in-human, Phase 1b, open-label, single-dose study.

JOR spine·2024

Health Insurance Coverage Predicts Health Care Use among Latine Immigrants in Two Policy Contexts.

Journal of health care for the poor and underserved·2024

A randomized, double-blinded, phase 2 trial of EDP1815, an oral immunomodulatory preparation of Prevotella histicola, in adults with mild-to-moderate plaque psoriasis.

Frontiers in medicine·2024

Association of ACE I/D polymorphism with blood pressure response to valsartan-hydrochlorothiazide combination therapy in hypertensive patients from Khyber Pakhtunkhwa, Pakistan.

Pharmacogenomics·2026

Impact of NAT2 acetylation phenotype on toxicity in tuberculosis therapy: a systematic review and meta-analysis.

Pharmacogenomics·2026

Evaluation of dopamine transporter gene variations in Turkish children with attention deficit hyperactivity disorder treated with methylphenidate adverse effects.

Pharmacogenomics·2026

Polygenic risk score and risk of drug-induced liver injury after initiating antiretroviral therapy in people living with HIV.

Pharmacogenomics·2026

Adherence to international pharmacogenomic recommendations in pediatric cancer care: a cohort analysis embedded within the MARVEL-PIC randomized trial.

Pharmacogenomics·2026

Closely similar tacrolimus morning troughs and graft function across the recipients' common ABCB1 polymorphisms (c.2677G>T/A, c.1236C>T, c.3435C>T) early after renal transplantation.

Pharmacogenomics·2026

Effectiveness of Anti-Osteoporotic Medications in the Management of Glucocorticoid-Induced Osteoporosis: A Systematic Review and Network Meta-Analysis on Behalf of the ECTS Clinical Action Group.

European journal of endocrinology·2026

Clinical and economic outcomes of cabazitaxel versus Lu-PSMA in mCRPC: a US perspective.

Journal of medical economics·2026

Differential P3 reactivity to pornographic versus natural rewards as a neural marker of reward imbalance in problematic pornography use in young heterosexual men.

International journal of clinical and health psychology : IJCHP·2026

Influence of adrenergic drugs and volume loading on mean systemic filling pressure in non-septic and septic sheep.

Frontiers in medicine·2026

The effect of PCSK9 inhibitors on cardiovascular outcomes in diabetic patients: a narrative review.

Frontiers in pharmacology·2026

Development and Characterization of a Long-Acting Allosteric Growth Hormone Receptor Antagonist for Acromegaly.

Endocrinology·2026

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Corrigendum to 'Intradiscal linezolid (PP353) treatment for chronic low back pain associated with Modic change type 1: an international, first-in-human, randomised, sham procedure-controlled, double-blind, phase 1b clinical trial' eClinicalMedicine 2026; 92: 103764.

Intradiscal linezolid (PP353) treatment for chronic low back pain associated with Modic change type 1: an international, first-in-human, randomised, sham procedure-controlled, double-blind, phase 1b clinical trial.

Phase 1/2, open-label study of oral bacterial supplementation (EDP1503) plus pembrolizumab in participants with advanced or metastatic microsatellite-stable colorectal cancer, triple-negative breast cancer, and checkpoint inhibitor-relapsed tumors.

Pharmacokinetics of PP353, a formulation of linezolid for intervertebral disc administration, in patients with chronic low back pain and Modic change Type 1: A first-in-human, Phase 1b, open-label, single-dose study.

Health Insurance Coverage Predicts Health Care Use among Latine Immigrants in Two Policy Contexts.

A randomized, double-blinded, phase 2 trial of EDP1815, an oral immunomodulatory preparation of Prevotella histicola, in adults with mild-to-moderate plaque psoriasis.

Association of ACE I/D polymorphism with blood pressure response to valsartan-hydrochlorothiazide combination therapy in hypertensive patients from Khyber Pakhtunkhwa, Pakistan.

Impact of NAT2 acetylation phenotype on toxicity in tuberculosis therapy: a systematic review and meta-analysis.

Evaluation of dopamine transporter gene variations in Turkish children with attention deficit hyperactivity disorder treated with methylphenidate adverse effects.

Polygenic risk score and risk of drug-induced liver injury after initiating antiretroviral therapy in people living with HIV.

Adherence to international pharmacogenomic recommendations in pediatric cancer care: a cohort analysis embedded within the MARVEL-PIC randomized trial.

Closely similar tacrolimus morning troughs and graft function across the recipients' common ABCB1 polymorphisms (c.2677G>T/A, c.1236C>T, c.3435C>T) early after renal transplantation.

Effectiveness of Anti-Osteoporotic Medications in the Management of Glucocorticoid-Induced Osteoporosis: A Systematic Review and Network Meta-Analysis on Behalf of the ECTS Clinical Action Group.

Clinical and economic outcomes of cabazitaxel versus Lu-PSMA in mCRPC: a US perspective.

Differential P3 reactivity to pornographic versus natural rewards as a neural marker of reward imbalance in problematic pornography use in young heterosexual men.

Influence of adrenergic drugs and volume loading on mean systemic filling pressure in non-septic and septic sheep.

The effect of PCSK9 inhibitors on cardiovascular outcomes in diabetic patients: a narrative review.

Development and Characterization of a Long-Acting Allosteric Growth Hormone Receptor Antagonist for Acromegaly.

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