Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunotherapy for prostate cancer.

R Jeffrey Karnes1, Christopher M Whelan, Eugene D Kwon

  • 1Southern Illinois University School of Medicine, Division of Urology, Sprngfield 62794, USA.

Current Pharmaceutical Design
|March 7, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal Tumor Mutation Burden Dynamics in Advanced Prostate Cancer Using Circulating Tumor DNA Profiling.

Clinical genitourinary cancer·2026
Same author

Salvage lymph node dissection in oligo-recurrent prostate cancer patients: Mapping patterns of recurrence and factors associated with disease progression.

Urologic oncology·2026
Same author

Outcomes of stereotactic body radiotherapy for supraclavicular lymph node metastasis among patients with metastatic prostate cancer.

Clinical and translational radiation oncology·2026
Same author

LuRa: Efficacy and Safety of Radium-223 Following [<sup>177</sup>Lu]Lu-PSMA-617 in Patients With Metastatic Castration-Resistant Prostate Cancer.

Clinical genitourinary cancer·2026
Same author

PSA Zero Radiographic Disease Progression on PSMA PET/CT.

Cancers·2026
Same author

Scrotal uptake on PSMA PET in prostate cancer: differentiating metastases from benign and physiologic findings using ultrasound correlation.

Abdominal radiology (New York)·2026

Novel immunotherapies offer new hope for advanced prostate cancer. Research focuses on targeting prostate antigens with vaccines and cell-based therapies to enhance the immune system

Area of Science:

  • Oncology
  • Immunology
  • Cancer Therapy

Background:

  • Advanced or recurrent prostate cancer lacks curative treatments.
  • Immunotherapy presents a promising systemic approach for prostate cancer management.
  • Identification of prostate tissue/tumor antigens enables targeted immune strategies.

Purpose of the Study:

  • To review recent advancements in immunotherapeutic strategies for prostate cancer.
  • To highlight novel methods for inducing and enhancing T cell-mediated responses against prostate tumors.

Main Methods:

  • Targeting prostate antigens with antibodies or T cells for tumor cell injury.
  • Developing vaccines using prostate antigens to induce T cell-mediated immunity.
  • Utilizing autologous dendritic cells loaded with prostate antigens.

Related Experiment Videos

  • Manipulating T cell costimulatory pathways in vivo.

    • Main Results:

    • Prostate-specific T cell activation can be induced using antigen-loaded dendritic cells.
    • In vivo modulation of costimulatory pathways enhances tumor-specific T cell responses.
    • These approaches show potential in treating prostate cancer and other malignancies.

    Conclusions:

    • Significant progress has been made in prostate cancer immunotherapy.
    • Targeting prostate antigens and enhancing T cell activation are key strategies.
    • Immunotherapy holds promise for future prostate cancer treatment.