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[Morphometric analysis of normal human sural nerves for systematic clinical application]
A Ohnishi1, M Ikeda, T Yamamoto
1Department of Neurology, School of Medicine, University of Occupational and Environmental Health, Kitakyshu, Japan.
Journal of UOEH
|June 1, 1991
Summary
This study establishes age-adjusted normative data for sural nerve morphometry. This is crucial for accurately assessing peripheral nerve disorders and their severity in clinical practice.
Area of Science:
- Neuroscience
- Pathology
Context:
- Peripheral nerve disorders require precise diagnostic tools.
- Sural nerve morphometry provides valuable insights into nerve health.
Purpose:
- To establish normative morphometric data for the human sural nerve.
- To correlate age with sural nerve fiber characteristics.
Summary:
- A morphometric analysis was conducted on 30 control sural nerves from individuals aged 13-83.
- Data included frequencies of abnormal myelinated fibers and densities of total, large, small myelinated, and unmyelinated fibers.
- Significant linear correlations were found between age and these fiber characteristics (P < 0.01).
Impact:
- Provides age-adjusted reference values for clinical evaluation of peripheral nerve pathology.
- Enhances the accuracy of diagnosing and determining the severity of nerve disorders.
- Facilitates more precise comparisons of diseased nerve data with healthy controls.