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Updated: Aug 11, 2026

Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids
Published on: April 13, 2022
On the evolution of the standard amino-acid alphabet
1Department of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA.
Abstract:
Although one standard amino-acid 'alphabet' is used by most organisms on Earth, the evolutionary cause(s) and significance of this alphabet remain elusive. Fresh insights into the origin of the alphabet are now emerging from disciplines as diverse as astrobiology, biochemical engineering and bioinformatics.
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