Related Experiment Video
Updated: Aug 11, 2026
Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy
Published on: September 27, 2024
Endovascular therapy for chronic mesenteric ischemia
Jose A Silva1, Christopher J White, Tyrone J Collins
1Department of Cardiology, Section of Gastroenterology, Ochsner Clinic Foundation, New Orleans, Louisiana 70461, USA. jsilva@ochsner.org
Insights
Percutaneous stent placement effectively treats chronic mesenteric ischemia (CMI), offering high success and symptom relief. This endovascular approach shows long-term results comparable to surgery but with lower risks.
Area of Science:
- Vascular surgery
- Interventional radiology
- Gastroenterology
Background:
- Chronic mesenteric ischemia (CMI) traditionally treated with surgery.
- Surgery for CMI has high complication and mortality rates.
Purpose of the Study:
- To evaluate outcomes of percutaneous stent revascularization for CMI.
- Compare endovascular treatment to historical surgical approaches.
Main Methods:
- 59 patients with CMI underwent stent placement in 79 mesenteric arteries.
- Clinical and anatomical follow-up (angiography/ultrasound) at >=6 months.
- 96% procedural success rate achieved.
Main Results:
- 88% of patients experienced symptom relief.
- At mean 38-month follow-up, 79% survival rate and 17% symptom recurrence.
- 29% restenosis rate observed, successfully treated with repeat procedures.
Conclusions:
- Percutaneous stenting for CMI offers high success and low complication rates.
- Long-term symptom relief and patency are comparable to surgical outcomes.
- Endovascular approach is preferred due to lower procedural morbidity and mortality.
Objectives:
We sought to describe the outcomes of a consecutive series of patients with chronic mesenteric ischemia (CMI) who were treated with percutaneous stent revascularization.
Background:
Historically, the treatment for CMI has been surgical revascularization. However, surgery carries a significant procedural complication rate and mortality.
Methods:
Fifty-nine consecutive patients with CMI underwent stent placement in 79 stenotic (>70%) mesenteric arteries. All patients had clinical follow-up and 90% had anatomical follow-up with angiography (computed tomography or conventional) or ultrasound at > or =6 months after the procedure.
Results:
Procedural success was obtained in 96% (76 of 79 arteries) and symptom relief occurred in 88% (50 patients). At a mean follow-up of 38 +/- 15 months (range, 6 to 112 months), 79% of the patients remained alive, and 17% (n = 10) experienced a recurrence of symptoms. Angiography or ultrasound obtained at 14+/- 5 months after the procedure demonstrated a restenosis rate of 29% (n = 20). All patients with recurrent symptoms had angiographic in-stent restenosis and were successfully revascularized percutaneously.
Conclusions:
Percutaneous stent placement for the treatment of CMI can be performed with a high procedural success and a low complication rate. The long-term freedom from symptoms and vascular patency are comparable with surgical results. The inherent lower procedural morbidity and mortality makes the endovascular approach the preferred revascularization technique for these patients.
Related Concept Videos
01:27Peripheral Artery Disease III: Interprofessional Care
01:29Venous Thrombosis III: Interprofessional Care