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Published on: December 11, 2016
Relation of pericardial effusion to degree of fractional shortening
Mohammad-Reza Movahed1, Yuji Saito, Mastaneh Ahmadi-Kashani
1Department of Medicine, Division of Cardiology, University of California, Irvine, USA.
Insights
Pericardial effusion is more common in patients with left ventricular (LV) dysfunction, specifically decreased fractional shortening (FS). However, moderate to severe effusions are not explained by reduced LV systolic function.
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Imaging
Background:
- Significant pericardial effusion prevalence in left ventricular (LV) dysfunction is largely unreported.
- Assessing pericardial effusion in relation to LV systolic function is crucial for understanding cardiac health.
Purpose of the Study:
- To evaluate the prevalence and severity of pericardial effusion in patients with decreased fractional shortening (FS).
- To correlate pericardial effusion occurrence and severity with the degree of LV dysfunction.
Main Methods:
- Retrospective analysis of 24,265 echocardiograms (1984-1998).
- Fractional shortening (FS) measured in 18,015 echocardiograms and stratified into four groups.
- Pericardial effusion visually categorized as mild, moderate, or severe.
Main Results:
- Pericardial effusion was present in 1,632 patients with measured FS.
- Effusion prevalence increased with decreased FS (8.4% to 14.4%, p <0.0001).
- Only mild pericardial effusion correlated with decreased FS; moderate to severe effusions were not explained by reduced LV systolic function.
Conclusions:
- Decreased left ventricular (LV) systolic function, indicated by reduced fractional shortening (FS), is associated with a higher prevalence of pericardial effusion.
- The presence of moderate to severe pericardial effusion in patients with LV dysfunction requires further investigation beyond systolic function assessment.
Abstract:
The prevalence of significant pericardial effusion in patients with left ventricular (LV) dysfunction has not been reported. The goal of this study was to evaluate the prevalence and severity of pericardial effusion in patients with decreased fractional shortening (FS) using a large echocardiographic database. A retrospective analysis of 24,265 echocardiograms performed at our institution from 1984 to 1998 was undertaken. FS was measured in 18,015 of the echocardiograms. The occurrence of pericardial effusion was correlated with the degree of FS, and FS was stratified into 4 groups: (1) >25%, (2) 17.5% to 25%, (3) 10% to 17.5%, and (4) <10%. On the basis of visual estimation, effusion was divided into 3 groups: mild, moderate, and severe. Pericardial effusion was present in 1,632 of the echocardiograms in which FS was measured. Pericardial effusion was significantly more common in patients with FS <25% and was correlated with the severity of decreased FS (group 1: 8.4%; group 2: 12.8%; group 3: 13.2%; group 4: 14.4%; p <0.0001). However, when categorizing pericardial effusion by severity, only mild pericardial effusion was correlated with decreased FS (group 1: 6.6%; group 2: 11.0%; group 3: 11.1%; group 4: 14.0%; p <0000.1). Our results indicate that the occurrence of moderate to severe pericardial effusion cannot be explained by a decrease in LV systolic function.
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