Relation of pericardial effusion to degree of fractional shortening

Mohammad-Reza Movahed1, Yuji Saito, Mastaneh Ahmadi-Kashani

  • 1Department of Medicine, Division of Cardiology, University of California, Irvine, USA.

Insights

Pericardial effusion is more common in patients with left ventricular (LV) dysfunction, specifically decreased fractional shortening (FS). However, moderate to severe effusions are not explained by reduced LV systolic function.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Imaging

Background:

  • Significant pericardial effusion prevalence in left ventricular (LV) dysfunction is largely unreported.
  • Assessing pericardial effusion in relation to LV systolic function is crucial for understanding cardiac health.

Purpose of the Study:

  • To evaluate the prevalence and severity of pericardial effusion in patients with decreased fractional shortening (FS).
  • To correlate pericardial effusion occurrence and severity with the degree of LV dysfunction.

Main Methods:

  • Retrospective analysis of 24,265 echocardiograms (1984-1998).
  • Fractional shortening (FS) measured in 18,015 echocardiograms and stratified into four groups.
  • Pericardial effusion visually categorized as mild, moderate, or severe.

Main Results:

  • Pericardial effusion was present in 1,632 patients with measured FS.
  • Effusion prevalence increased with decreased FS (8.4% to 14.4%, p <0.0001).
  • Only mild pericardial effusion correlated with decreased FS; moderate to severe effusions were not explained by reduced LV systolic function.

Conclusions:

  • Decreased left ventricular (LV) systolic function, indicated by reduced fractional shortening (FS), is associated with a higher prevalence of pericardial effusion.
  • The presence of moderate to severe pericardial effusion in patients with LV dysfunction requires further investigation beyond systolic function assessment.

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