Hallucinations after hypospadias repair

Hubert S Swana1, Sharon L Youmans, Barry A Kogan

  • 1Department of Urology, University of California at San Francisco, San Francisco, CA 94143, USA.

Insights

A child experienced hallucinations after hypospadias repair due to oxybutynin overdose, diagnosed as central anticholinergic syndrome. Clear medication instructions for parents are crucial to prevent adverse drug events in pediatric patients.

Area of Science:

  • Pediatric Surgery
  • Pediatric Emergency Medicine
  • Clinical Toxicology

Background:

  • Hypospadias repair is a common pediatric surgical procedure.
  • Central anticholinergic syndrome is a potential adverse effect of certain medications.
  • Accurate medication dosing and administration are critical in pediatric care.

Observation:

  • A 4-year-old child developed hallucinations post-hypospadias repair.
  • The child presented to the emergency department with symptoms consistent with anticholinergic toxicity.
  • Central anticholinergic syndrome was diagnosed following outpatient surgery.

Findings:

  • The case highlights oxybutynin overdose as a cause of central anticholinergic syndrome in children.
  • Hallucinations and behavioral changes can be indicative of medication toxicity.
  • Postoperative medication management requires careful attention to dosage and administration.

Implications:

  • Emphasizes the need for clear, concise medication instructions for parents and caregivers.
  • Underscores the importance of educating families about potential side effects of prescribed medications.
  • Highlights the role of emergency departments in diagnosing and managing medication-related adverse events in children.

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