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Positron emission tomography/computed tomography: protocol issues and options.

Todd M Blodgett1, Barry M McCook, Michael P Federle

  • 1Department of Radiology, University of Pittsburgh Medical Center, PA 15213, USA. toddblodgett@yahoo.com

Seminars in Nuclear Medicine
|March 7, 2006
PubMed
Summary
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Combined positron emission tomography/computed tomography (PET/CT) offers advantages in accuracy and efficiency. Optimizing imaging protocols, including contrast use, enhances diagnostic value for various tumors.

Area of Science:

  • Radiology
  • Nuclear Medicine
  • Medical Imaging

Background:

  • Combined positron emission tomography/computed tomography (PET/CT) gained FDA approval in 2001.
  • Integrated PET/CT systems offer superior co-registration, lesion localization, and reduced scan times compared to separate PET and CT acquisitions.
  • Various scanning protocols exist for combined PET/CT devices.

Purpose of the Study:

  • To discuss protocols for combined PET/CT imaging.
  • To explore optimization of the CT component in PET/CT scans.
  • To address interpretation and reporting considerations for PET/CT.

Main Methods:

  • Review of established and potential protocols for combined PET/CT imaging.
  • Discussion on the role and optimization of contrast media (oral and intravenous) in the CT component.

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  • Consideration of clinical variables influencing protocol selection, such as tumor type and location.

    • Main Results:

    • Combined PET/CT provides enhanced accuracy and efficiency in oncologic imaging.
    • Contrast media can improve the diagnostic utility of the CT portion, particularly in abdominal and pelvic malignancy detection.
    • Protocol selection is dependent on specific clinical scenarios and diagnostic goals.

    Conclusions:

    • Combined PET/CT is a valuable tool in modern diagnostics.
    • Optimized protocols, including judicious use of contrast, maximize the diagnostic yield of PET/CT.
    • Standardized approaches to interpretation and reporting are crucial for consistent clinical application.